Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- Recruiting
Hyrax Vs. Invisalign Palatal Expander Clinical Study
Align Technology, Inc.
- Location
- Laguna Hills, CA + 3 other US sites
- Eligibility basics
- Ages 6–11
- Recruiting
Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD
VisionCare, Inc.
- Location
- Loma Linda, CA + 9 other US sites
- Eligibility basics
- Ages 65+
- Recruiting
LIMBER UniLeg: Rapid, On-demand, and Scaled-up Manufacturing of Customized Transtibial Prosthetic Legs for Amputees
LIMBER Prosthetics & Orthotics Inc
- Location
- La Jolla, CA + 1 other US site
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
Treatment of Radiation and Cisplatin Induced Toxicities with Tempol
Matrix Biomed, Inc.
- Location
- La Jolla, CA + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Imaging Immune Activation in HIV by PET-MR
CellSight Technologies, Inc.
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18+
- Recruiting
Adipose-Derived Biocellular Regenerative Therapy for Osteoarthritis
Healeon Medical Inc
- Location
- Valencia, CA
- Eligibility basics
- Ages 18–90
- RecruitingEarly Phase 1
Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Knee Osteoarthritis
R3 Medical Research
- Location
- Beverly Hills, CA + 4 other US sites
- Eligibility basics
- Ages 30+
- Recruiting
Encore PFO Closure Device - The PerFOrm Trial
Encore Medical Inc.
- Location
- La Jolla, CA + 7 other US sites
- Eligibility basics
- Ages 18–60
- RecruitingPhase 1/Phase 2
Pharmacokinetics, Safety, Tolerability of Dolutegravir/Rilpivirine in Pediatrics
ViiV Healthcare
- Location
- Long Beach, CA + 5 other US sites
- Eligibility basics
- Ages 6–12
- Recruiting
Computer-Assisted Hair Restoration Study Using ARTAS System
Venus Concept
- Location
- San Jose, CA
- Eligibility basics
- Ages 20–70 · Men only
- Recruiting
ConsideRAte Study - Splenic Stimulation for RA
Galvani Bioelectronics
- Location
- Covina, CA + 9 other US sites
- Eligibility basics
- Ages 22–75
- Recruiting
PARTNER 3 Trial - Aortic Valve-in-Valve
Edwards Lifesciences
- Location
- Los Angeles, CA + 28 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 1
Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar Pain
R3 Stem Cell
- Location
- Beverly Hills, CA + 3 other US sites
- Eligibility basics
- Ages 20+
- RecruitingPhase 1/Phase 2
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction
Sardocor Corp.
- Location
- San Diego, CA + 4 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
Phase 2 Clinical Trial of CartiLife® in the United States
Biosolution Co., Ltd.
- Location
- La Mesa, CA + 3 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
A Clinical Investigation to Follow the Progress of Exuding Chronic Wounds Using Mepilex® Up as the Primary Dressing.
Molnlycke Health Care AB
- Location
- Castro Valley, CA + 3 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Physica System Total Knee Replacement Registry Study
Limacorporate S.p.a
- Location
- Rancho Mirage, CA + 2 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 3
Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.
Amneal Pharmaceuticals, LLC
- Location
- Newport Beach, CA + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
An Adaptive Phase II/III, Two-Part, Double-Blind, Randomized, Placebo-controlled, Dose-Finding, Multi-center Study of the Safety and Efficacy of NaBen®, as an Add-on Therapy With Clozapine, for Residual Symptoms of…
SyneuRx International (Taiwan) Corp
- Location
- Pasadena, CA
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteers
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others
Michael Shy
- Location
- Los Angeles, CA + 17 other US sites
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteers
Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network
National Human Genome Research Institute (NHGRI)
- Location
- Los Angeles, CA + 23 other US sites
- Eligibility basics
- Ages 1 mo–100
- RecruitingHealthy volunteers
Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy
National Cancer Institute (NCI)
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 5+
- RecruitingHealthy volunteers
Neurophysiologic Biomarkers in Rett Syndrome
Children's Hospital of Philadelphia
- Location
- Los Angeles, CA + 5 other US sites
- Eligibility basics
- Ages 1–18 · Women only
- RecruitingHealthy volunteersPhase 2
CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant
City of Hope Medical Center
- Location
- Duarte, CA + 2 other US sites
- Eligibility basics
- Ages 18–75