Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 3
A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With CKD Stage 3b and 4 (BalanceD-CKD)
AstraZeneca
- Location
- Concord, CA + 9 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 2
ORKA-002 Versus Placebo in Participants With Moderate-to-Severe Hidradenitis Suppurativa
Oruka Therapeutics, Inc.
- Location
- Fountain Valley, CA + 13 other US sites
- Eligibility basics
- Ages 18–79
- RecruitingPhase 1
A Phase 1 Study of VK2735 in Obese Adults Without Comorbidities
Viking Therapeutics, Inc.
- Location
- Lake Forest, CA + 1 other US site
- Eligibility basics
- Ages 18–60
- RecruitingPhase 2
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
Eli Lilly and Company
- Location
- Palm Springs, CA + 34 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction
Sanofi
- Location
- Los Angeles, CA + 31 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
A Study to Test a Medicine (Fitusiran) for Preventing Bleeds in People With Severe Hemophilia Who Previously Received Preventive Treatment With Emicizumab
Sanofi
- Location
- Los Angeles, CA + 1 other US site
- Eligibility basics
- Ages 12+ · Men only
- RecruitingPhase 2
To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension
E-Star BioTech, LLC
- Location
- Lake Forest, CA + 21 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
A Phase IIb Randomized, Multicenter Trial of Subretinal CPCB-RPE1 in Advanced Dry AMD (Geographic Atrophy)
Regenerative Patch Technologies, LLC
- Location
- Huntington Beach, CA + 4 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 1
A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants With Amyotrophic Lateral Sclerosis (ALS)
Insmed Gene Therapy LLC
- Location
- La Jolla, CA + 6 other US sites
- Eligibility basics
- Ages 18–79
- RecruitingPhase 2
Study of DISC-0974-201 in Participants With IBD and Anemia
Disc Medicine, Inc
- Location
- Los Angeles, CA + 14 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate Efficacy and Safety of YSBP Compared to Lumigan in Patients With Glaucoma or Ocular Hypertension
YS Life Science Co., Ltd.
- Location
- Newport Beach, CA
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Study of GS-0415 and How It Works in People With HIV
Gilead Sciences
- Location
- Los Angeles, CA + 14 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
A Study to Learn How Different Amounts of the Study Medicine Called PF-08642534 Are Tolerated and Act in the Body of People Who Have Obesity
Pfizer
- Location
- Lake Forest, CA
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
Phase 3 Study of the Efficacy, Safety, and Clinical Outcomes of Pemvidutide in MASH
Altimmune, Inc.
- Location
- Fountain Valley, CA + 8 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Hydrus® Microstent New Enrollment Post-Approval Study
Alcon Research
- Location
- Sacramento, CA + 12 other US sites
- Eligibility basics
- Ages 45+
- RecruitingPhase 3
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Location
- Anaheim, CA + 43 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 2
A Study of Belumosudil in Children With Chronic Graft Versus Host Disease (schoolROCK)
Sanofi
- Location
- Los Angeles, CA + 6 other US sites
- Eligibility basics
- Ages 1–18
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
Eli Lilly and Company
- Location
- Escondido, CA + 40 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease
Novartis Pharmaceuticals
- Location
- La Jolla, CA + 39 other US sites
- Eligibility basics
- Ages 21–70
- Recruiting
A U.S. Pilot Human Investigation of RadiofrEquency Vapor Ablation System to Evaluate Safety, TOleRability, and Effectiveness for Proximal Intestinal Mucosal Ablation in Patients With Type 2 Diabetes Mellitus (RESTORE-1…
Aqua Medical, Inc.
- Location
- Newport Beach, CA + 3 other US sites
- Eligibility basics
- Ages 22–65
- RecruitingPhase 3
Open Label Study to Investigate the Safety and Efficacy of Ponesimod in Moderate-to-Severe Chronic Plaque Psoriasis
Vanda Pharmaceuticals
- Location
- Fremont, CA + 9 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
Eli Lilly and Company
- Location
- Irvine, CA + 55 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Investigate Abdominal Symptoms With Camlipixant Compared With Placebo in Adults With Irritable Bowel Syndrome - Diarrhea (IBS-D) and Irritable Bowel Syndrome - Mixed (IBS-M)
GlaxoSmithKline
- Location
- Anaheim, CA + 93 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight
AstraZeneca
- Location
- Lincoln, CA + 4 other US sites
- Eligibility basics
- Ages 18+