Healthy volunteers · Minnesota
Studies for healthy volunteers in Minnesota
223 studies have at least one recruiting site in Minnesota. These studies say in their official record that they accept healthy volunteers. Many are Phase 1 studies that test how a new medicine is absorbed and tolerated; others recruit healthy people as a comparison group alongside patients.
223 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteers
Ultrasound With Subharmonic Imaging and Subharmonic Aided Pressure Estimation (SHAPE) to Identify Portal Hypertension
Mayo Clinic
- Location
- Rochester, MN + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Sleep Restriction and Parental History of Hypertension
Mayo Clinic
- Location
- Rochester, MN
- Eligibility basics
- Ages 18–35
- RecruitingHealthy volunteers
Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma
Case Western Reserve University
- Location
- Rochester, MN + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Metabolic and Physiologic Responses to Hormone Therapy in Transgender and Gender Diverse People
Mayo Clinic
- Location
- Rochester, MN
- Eligibility basics
- Ages 18–40
- RecruitingHealthy volunteers
Prospective Assessment of HPV Associated Anogenital Pathology in Female Patients and Female Partners of Patients With Confirmed HPV Associated Oropharyngeal Carcinoma, PAP-OP Study
Mayo Clinic
- Location
- Rochester, MN
- Eligibility basics
- Ages 18+ · Women only
- RecruitingHealthy volunteers
A Comparison of Neuromuscular Recruitment in Trained and Untrained Adults
Mayo Clinic
- Location
- Rochester, MN
- Eligibility basics
- Ages 60–85
- RecruitingHealthy volunteers
Upper Body Subcutaneous Exosome Release in Response to a Meal in Obesity
Mayo Clinic
- Location
- Rochester, MN
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteers
Evaluation of Decision-Making Fatigue After Traumatic Brain Injury
University of Minnesota
- Location
- Minneapolis, MN
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
The Effects of Sleep on Human Microbiota: Implications for Health and Disease
Mayo Clinic
- Location
- Rochester, MN
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S04)
National Cancer Institute (NCI)
- Location
- Minneapolis, MN + 17 other US sites
- Eligibility basics
- Ages 25+ · Women only
- RecruitingHealthy volunteers
Tissue Destruction and Healing in Celiac Disease
University of Chicago
- Location
- Rochester, MN + 1 other US site
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteers
Rural Smoking Cessation
Masonic Cancer Center, University of Minnesota
- Location
- Minneapolis, MN
- Eligibility basics
- Ages 21+
- RecruitingHealthy volunteers
Role of Acetaldehyde in the Development of Oral Cancer
Masonic Cancer Center, University of Minnesota
- Location
- Minneapolis, MN
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteers
A Study of TopSpin360 Training Device
Mayo Clinic
- Location
- Rochester, MN
- Eligibility basics
- Ages 18–21
- RecruitingHealthy volunteers
Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms
University of Minnesota
- Location
- Minneapolis, MN
- Eligibility basics
- Ages 21–70
- RecruitingHealthy volunteers
A Study to Evaluate Breathing Muscle Training in Cardiac Rehab
Mayo Clinic
- Location
- Rochester, MN
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Comprehensive HHT Outcomes Registry of the United States (CHORUS)
Cure HHT
- Location
- Rochester, MN + 15 other US sites
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteers
Imaging Studies in Corticobasal Syndrome
Jennifer Whitwell
- Location
- Rochester, MN
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Time-Efficient Inspiratory Muscle Strength Training for Reducing Sympathetic Activity and Improving Sleep in Midlife Women
Mayo Clinic
- Location
- Rochester, MN
- Eligibility basics
- Ages 45–60 · Women only
- RecruitingHealthy volunteers
Acceptability of Testing DNA Markers in Vaginal Fluid for the Detection of Endometrial Cancer
Mayo Clinic
- Location
- Rochester, MN
- Eligibility basics
- Ages 45+ · Women only
- RecruitingHealthy volunteers
Visual Remapping to Aid Reading With Field Loss
University of Minnesota
- Location
- Minneapolis, MN
- Eligibility basics
- Ages 16+
- RecruitingHealthy volunteers
Evaluation of a Novel Auto Segmentation Algorithm for Normal Structure Delineation in Radiation Treatment Planning
Mayo Clinic
- Location
- Albert Lea, MN + 6 other US sites
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteers
American Indian Smokefree Native RCT
Masonic Cancer Center, University of Minnesota
- Location
- Minneapolis, MN
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 2
A Study of 68Ga-Fibroblast Activation Protein Inhibitor (FAPI) Positron Emission Tomography in Heart Failure
Mayo Clinic
- Location
- Rochester, MN
- Eligibility basics
- Ages 18+
Who these studies look for
“Healthy” is decided at screening, not by you. Sites usually check vital signs, blood and urine tests, an ECG, your medications and sometimes your BMI or smoking status. A study can still turn you away for reasons that have nothing to do with being unwell, such as timing or a full roster.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do healthy volunteer studies pay?
Many do, because volunteers give up time and follow strict schedules, but amounts are set by each study and are usually only confirmed by the research site. When a record states an amount we show the exact wording; otherwise we say compensation is not disclosed.
What happens at a screening visit?
Expect consent paperwork first, then a health questionnaire, vital signs, blood and urine samples and often an ECG. You can ask questions and withdraw at any time, before or after you sign.