Mental health · California
Mental health studies in California
146 studies have at least one recruiting site in California. Mental health research includes studies of depression, anxiety, PTSD, bipolar disorder, schizophrenia and ADHD, testing medicines, devices and talk therapies.
146 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingHealthy volunteers
Implementation Supports to Reduce Burnout in Therapists Delivering Child Trauma EBPs
San Diego State University
- Location
- San Diego, CA
- Eligibility basics
- Ages 3–99
- RecruitingHealthy volunteers
Positive Affect Treatment for Adolescents With Early Life Adversity
University of California, Irvine
- Location
- Irvine, CA
- Eligibility basics
- Ages 12–16
- RecruitingHealthy volunteersPhase 2
Regulation of Affect and Physiology in Depression
University of Southern California
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 18–27
- RecruitingHealthy volunteers
ACT Group for Family Caregivers of Stroke Survivors
The Wright Institute
- Location
- Alameda, CA
- Eligibility basics
- Ages 40+
- RecruitingHealthy volunteers
Effect of Ashwagandha Root Extract on Stress, Anxiety, and Sleep Quality in Adults Experiencing Minority Stress
SF Research Institute, Inc.
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteersPhase 2
Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)
Stanford University
- Location
- Stanford, CA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
Brief Behavioral Treatment for Insomnia in Veterans With Posttraumatic Stress Disorder
VA Office of Research and Development
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteers
Hybrid Effectiveness-Implementation Trial of an Executive Functioning Intervention for Children's Mental Health Services
San Diego State University
- Location
- San Diego, CA + 1 other US site
- Eligibility basics
- Ages 6–99
- RecruitingHealthy volunteersPhase 2
Sleep Health in U.S. Marines
San Diego State University
- Location
- San Diego, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder
University of California, Los Angeles
- Location
- North Hills, CA
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
Effects of Brain Stimulation on Cognition, Oscillations and GABA Levels in Schizophrenia
University of California, Davis
- Location
- Sacramento, CA
- Eligibility basics
- Ages 18–47
- RecruitingHealthy volunteers
Sleep Well Firefighters: An App-based Program to Improve Sleep, Cognition, and Behavioral Health in Firefighters
California Polytechnic State University-San Luis Obispo
- Location
- San Luis Obispo, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Students Rising Above: Offsetting the Health and Mental Health Costs of Resilience
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 13+
- RecruitingHealthy volunteers
Brain Stimulation to the Hippocampus in Schizophrenia
Stanford University
- Location
- Stanford, CA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
Optimizing Brain Excitability in Depression
Stanford University
- Location
- Iowa City, CA + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
Filipino Family Health Initiative 1.0
Kaiser Permanente
- Location
- Pasadena, CA
- Eligibility basics
- Ages 8+
- RecruitingHealthy volunteers
Efficacy of Lavender Aromatherapy on Anxiety and Pain Reduction During Awake Otolaryngologic Procedures
Cedars-Sinai Medical Center
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
RCT for Latina Mental Health Using Web-Based Apps
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 18+ · Women only
- RecruitingHealthy volunteers
Virtual Reality Interventions for the Improvement of Depression, Anxiety and Pain in Patients With Head and Neck Cancer and Caregivers
City of Hope Medical Center
- Location
- Duarte, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Neurophysiologic Biomarkers for Cognitive Rehabilitation
VA Office of Research and Development
- Location
- San Diego, CA
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteers
Sensory Adapted Dental Environments to Enhance Oral Care for Children With and Without Dental Fear and Anxiety
University of Southern California
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 6–12
- RecruitingHealthy volunteers
Novel Multimodal Neural, Physiological, and Behavioral Sensing and Machine Learning for Mental States
University of Southern California
- Location
- Downey, CA + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Medial-prefrontal Enhancement During Schizophrenia Systems Imaging
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteers
Efficacy and Safety of a Proprietary Blend of Ashwagandha Root Extract (Aqueous) in Adult Men and Women With High Stress and Anxiety: A Randomized, Double-blind, Three-arm, Parallel, Placebo-controlled Study
SF Research Institute, Inc.
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–65
Who these studies look for
Studies usually require a confirmed diagnosis and stable circumstances, and they monitor safety closely. If you are in crisis, contact a crisis line or emergency services rather than a study.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Will joining affect my current treatment?
Some studies require changes to medicines, which the study team manages; others add to your usual care. Talk to your own clinician before making any change.