Study type
Smoking and vaping studies recruiting now
Tobacco research includes quit-smoking and quit-vaping programs, new cessation medicines and studies of how nicotine products affect the body.
161 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteers
Healthy Family Project: Tobacco Use and Smoke Exposure in Asian American Communities
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Influence of Authorized Smokeless Tobacco Product Modified Risk Claims I: Consumer Product Demand
Roswell Park Cancer Institute
- Location
- Buffalo, NY
- Eligibility basics
- Ages 21+
- RecruitingHealthy volunteers
Support and Outreach to Increase Screening for Lung Cancer in Patients With a History of Smoking
Ronald Myers
- Location
- Philadelphia, PA
- Eligibility basics
- Ages 50–77
- RecruitingHealthy volunteers
The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study
Memorial Sloan Kettering Cancer Center
- Location
- New York, NY
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Influence of Authorized Smokeless Tobacco Product Modified Risk Claims II: Laboratory Assessment of Sensory and Subjective Effects
Roswell Park Cancer Institute
- Location
- Buffalo, NY
- Eligibility basics
- Ages 21+
- RecruitingHealthy volunteers
Testing an MBI for Smoking Cessation and Alcohol Use Among Cancer Survivors
H. Lee Moffitt Cancer Center and Research Institute
- Location
- Tampa, FL
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Early Detection of Vaping-related Vascular Diseases
University of Miami
- Location
- Miami, FL
- Eligibility basics
- Ages 18–40
- RecruitingHealthy volunteersPhase 3
Community-based Smoking Cessation Treatment for Adults With High Stress Sensitivity.
Jasper A. Smits
- Location
- Austin, TX
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Developing a Scalable Tobacco Cessation Program for Cancer Survivors and Caregivers
University of Florida
- Location
- Gainesville, FL
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 2/Phase 3
Empowering Cessation ACS South Region
University of Oklahoma
- Location
- Oklahoma City, OK
- Eligibility basics
- Ages 18–100
- RecruitingHealthy volunteers
Cigar Legislation and Regulation in Tobacco for the Young (Project CLARITY)
University of Oklahoma
- Location
- Oklahoma City, OK
- Eligibility basics
- Ages 18–24
- RecruitingHealthy volunteers
Lung Cancer Biomarkers and Screening
NYU Langone Health
- Location
- New York, NY
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
Linking Brain Network Dynamics to Imminent Smoking Lapse Risk and Behavior
Penn State University
- Location
- University Park, PA
- Eligibility basics
- Ages 21–65
- RecruitingHealthy volunteersPhase 3
Integrating Financial Coaching and Smoking Cessation Coaching
NYU Langone Health
- Location
- New York, NY
- Eligibility basics
- Ages 18–100
- RecruitingHealthy volunteers
A Culturally Tailored Smartphone Application for African American Smokers
University of Oklahoma
- Location
- Oklahoma City, OK
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 4
Woodsmoke Exposure, Influenza Infection, and Nasal Immunity
University of North Carolina, Chapel Hill
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 18–49
- RecruitingHealthy volunteersPhase 2
Dyadic Financial Incentive Treatments for Dual Smoker Couples
University of Oklahoma
- Location
- Tulsa, OK
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 4
Beta-Adrenergic Modulation of Drug Cue Reactivity
University of Oklahoma
- Location
- Tulsa, OK
- Eligibility basics
- Ages 21–60
- RecruitingHealthy volunteers
Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults
University of Chicago
- Location
- Chicago, IL
- Eligibility basics
- Ages 18–26
- RecruitingHealthy volunteers
Smoke Free SafeCare: Establishing a Smoke Free Home in CPS-involved Families
Georgia State University
- Location
- Atlanta, GA
- Eligibility basics
- Ages 18–89
- RecruitingHealthy volunteers
Trial of a Harm Reduction Strategy for People With HIV Who Smoke Cigarettes
Montefiore Medical Center
- Location
- The Bronx, NY
- Eligibility basics
- Ages 40–79
- RecruitingHealthy volunteers
Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia
University of Virginia
- Location
- Charlottesville, VA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
RTMS Targets Neural Circuits for Smoking Cessation
Medical University of South Carolina
- Location
- Charleston, SC
- Eligibility basics
- Ages 22–70
- RecruitingHealthy volunteers
Menthol, Inflammation, and Nicotine Transition Study
Rosalind Franklin University of Medicine and Science
- Location
- North Chicago, IL
- Eligibility basics
- Ages 21–85
Who these studies look for
Most require current smoking or vaping at a set level, measured at screening. Quit studies often include counseling.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do I have to quit to join?
Cessation studies are for people who want to quit. Other tobacco studies may ask you to keep your usual habits or switch products for a period. The listing explains which.