Study type
Smoking and vaping studies recruiting now
Tobacco research includes quit-smoking and quit-vaping programs, new cessation medicines and studies of how nicotine products affect the body.
161 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteers
Effects of E-cigarette Use on Health
University of Wisconsin, Madison
- Location
- Madison, WI
- Eligibility basics
- Ages 21+
- RecruitingHealthy volunteers
Studying Flavors and Cooling Agents in Oral Nicotine Pouches to Understand User Preferences
Ohio State University Comprehensive Cancer Center
- Location
- Columbus, OH
- Eligibility basics
- Ages 21+
- RecruitingHealthy volunteers
A Smoke-Free Home Intervention in Tribal Communities
Emory University
- Location
- Atlanta, GA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Studying the Effects of Nicotine Concentration and Flavor on Alcohol Use in Young Adults
Ohio State University Comprehensive Cancer Center
- Location
- Columbus, OH
- Eligibility basics
- Ages 21–30
- RecruitingHealthy volunteers
Communicating About Nicotine Reduction in Cigarettes
Georgia State University
- Location
- Atlanta, GA + 1 other US site
- Eligibility basics
- Ages 21+
- RecruitingHealthy volunteersPhase 4
Addiction Potential of Very Low Nicotine Filtered Little Cigars
Ohio State University Comprehensive Cancer Center
- Location
- Columbus, OH
- Eligibility basics
- Ages 21–75
- RecruitingHealthy volunteers
Attitudes and Perceptions Attitudes and Smoking Perceptions in the Real Environment -II
University of Oklahoma
- Location
- Oklahoma City, OK
- Eligibility basics
- Ages 18–34
- RecruitingHealthy volunteers
Healing Within: Mindfulness Smoking Cessation Intervention
National Heart, Lung, and Blood Institute (NHLBI)
- Location
- Rapid City, SD
- Eligibility basics
- Ages 18+ · Women only
- RecruitingHealthy volunteers
Vape-Free Text-Messaging: Pilot Study
Jovan Gwon, PhD, RN, FIAAN
- Location
- Milwaukee, WI
- Eligibility basics
- Ages 18–24
- RecruitingHealthy volunteersPhase 4
PET Imaging Using the Tracer [18F]VAT to Assess the Antidepressant Effect of Nicotine.
Stony Brook University
- Location
- Stony Brook, NY
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
Effects of a Specific Substance in Smokers
Oregon Health and Science University
- Location
- Portland, OR
- Eligibility basics
- Ages 21–40
- RecruitingHealthy volunteers
Pilot Study of the YES-CAN! Program to Prevent Youth Nicotine Vaping
University of Colorado, Denver
- Location
- Aurora, CO
- Eligibility basics
- Ages 9+
- RecruitingHealthy volunteersPhase 2
Nicotine Regulation for Dual Users of E-cigarettes and Cigarettes
University of Vermont
- Location
- Providence, RI + 1 other US site
- Eligibility basics
- Ages 21+
- RecruitingHealthy volunteers
Perceptual Influences From Smoking Cannabis: an Experimental Study
University of Colorado, Boulder
- Location
- Boulder, CO
- Eligibility basics
- Ages 21–65
- RecruitingHealthy volunteers
New Strategies to Enhance Smoking Cessation
University of Chicago
- Location
- Chicago, IL
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteers
Smoke-free Home Study in Subsidized Housing
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Chronic Cannabis Smoking, Oxidative Stress and the Pulmonary Innate Immune Response
University of Colorado, Denver
- Location
- Aurora, CO
- Eligibility basics
- Ages 18–55
Who these studies look for
Most require current smoking or vaping at a set level, measured at screening. Quit studies often include counseling.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do I have to quit to join?
Cessation studies are for people who want to quit. Other tobacco studies may ask you to keep your usual habits or switch products for a period. The listing explains which.