Who can join
Studies for adults 50 and older
These studies set a minimum age of 50 or older in their official record. Many look at conditions more common with age, and some vaccine and memory studies specifically need older participants.
417 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 2
The Role of Sirolimus in Preventing Functional Decline in Older Adults
Irina Timofte
- Location
- Dallas, TX
- Eligibility basics
- Ages 65–80
- RecruitingHealthy volunteers
Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People at Risk for Alzheimer's Disease
Massachusetts General Hospital
- Location
- Boston, MA + 1 other US site
- Eligibility basics
- Ages 55–90
- RecruitingHealthy volunteers
e-ALIGN: A Patient Portal-based Intervention to Align Medications With What Matters Most
Johns Hopkins University
- Location
- Baltimore, MD
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
A Pilot Study to Evaluate PureWick for Nocturia
Northwell Health
- Location
- Syosset, NY
- Eligibility basics
- Ages 50+ · Women only
- RecruitingHealthy volunteers
Interactive Effects of Sodium and Potassium on Vascular Health in Older Adults
Florida State University
- Location
- Tallahassee, FL
- Eligibility basics
- Ages 55–75
- RecruitingHealthy volunteers
Healthy Aging in People With Epilepsy Program
Anny Reyes
- Location
- Cleveland, OH
- Eligibility basics
- Ages 55–90
- RecruitingHealthy volunteers
Polyphenols and Cognitive Decline
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
Village-Integrated Eye Worker Trial II
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteers
Investigation of Inflammation in Alzheimer's Disease and Related Dementias (ADRD) Using [11C]-CS1P1
Washington University School of Medicine
- Location
- St Louis, MO
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
Skeletal Muscle Energetics and Fatiguability in Older Individuals
Johns Hopkins University
- Location
- Baltimore, MD
- Eligibility basics
- Ages 60–90
- RecruitingHealthy volunteers
Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis
Columbia University
- Location
- Beverly Hills, CA + 4 other US sites
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
Spinal Networks of Balance Learning and Retention in Older Adults
University of Florida
- Location
- Gainesville, FL
- Eligibility basics
- Ages 65–95
- RecruitingHealthy volunteers
Physical and Cognitive Aging Study in Older Adults
University of Florida
- Location
- Jacksonville, FL
- Eligibility basics
- Ages 55–85
- RecruitingHealthy volunteers
Pharyngeal Exercise (Plus Protein)
NYU Langone Health
- Location
- New York, NY + 1 other US site
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
Improving Adult Protective Services Client Outcomes: A Stepped-Care Social and Mental Health Engagement Program
The University of Texas Health Science Center, Houston
- Location
- Houston, TX
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
Assessing the Influence of Habitual Beef Intake on Key Molecular Markers of Brain Health
South Dakota State University
- Location
- Brookings, SD
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
Effect of Gerofit Exercise on Cognition in Older Veterans
VA Office of Research and Development
- Location
- West Los Angeles, CA + 1 other US site
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
CAPABLE Care + Connect
Johns Hopkins University
- Location
- Baltimore, MD
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
Reducing Blood Pressure in Mid-life Adult Binge Drinkers
The University of Texas at Arlington
- Location
- Arlington, TX
- Eligibility basics
- Ages 50–64
- RecruitingHealthy volunteers
Support and Outreach to Increase Screening for Lung Cancer in Patients With a History of Smoking
Ronald Myers
- Location
- Philadelphia, PA
- Eligibility basics
- Ages 50–77
- RecruitingHealthy volunteers
The INSPIRE -Faith Study: Intervention Strategies for Preserving Intellectual Resilience and Engagement
Healthy Minds Initiative
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 55–85
- RecruitingHealthy volunteers
Effects of Collagen Peptide Supplementation on Connective Tissue Remodeling, Functional Outcomes, and Wound Healing After Total Knee Arthroplasty (TKA)
University of Arkansas
- Location
- Little Rock, AR
- Eligibility basics
- Ages 50–75
- RecruitingHealthy volunteers
Mode of Exercise and Bone Biomarkers in Older Veterans
VA Office of Research and Development
- Location
- Aurora, CO
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteers
Caregiver Stress and Sleep Study
University of Pittsburgh
- Location
- Pittsburgh, PA
- Eligibility basics
- Ages 55+
Questions
If I fit this group, will I qualify?
Not necessarily. Age and sex limits are only the first filter. Each study has its own inclusion and exclusion criteria, and the research team decides at screening.
Where do these age and sex limits come from?
From the eligibility section of each study’s official ClinicalTrials.gov record. We don’t infer eligibility from anything else.