Who can join
Studies for adults 50 and older
These studies set a minimum age of 50 or older in their official record. Many look at conditions more common with age, and some vaccine and memory studies specifically need older participants.
417 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteers
Social Disconnection Study
Yale University
- Location
- New Haven, CT
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteers
Using Virtual Reality Travel to Reduce Loneliness in Older Adults
Indiana University
- Location
- Bloomington, IN + 2 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
Evaluating the Impact of CONNECT in a Multilingual Population
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 50–80
- RecruitingHealthy volunteers
Use of a Mobile Brain-Body Imaging Approach to Evaluate the Effects of Rhythmic Auditory Stimulation on Gait and Brain Function in Alzheimer's Disease
Boston University Charles River Campus
- Location
- Boston, MA
- Eligibility basics
- Ages 50–90
- RecruitingHealthy volunteersPhase 2
UAB Alzheimer's Disease Center Core Cohort - Imaging Substudy
University of Alabama at Birmingham
- Location
- Birmingham, AL
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteersPhase 2
The Mito-Frail Trial: Effects of MitoQ on Vasodilation, Mobility and Cognitive Performance in Frail Older Adults
UConn Health
- Location
- Farmington, CT
- Eligibility basics
- Ages 65–80
- RecruitingHealthy volunteers
Effects of Freeze-dried Grape Powder on Immune Profiles in Healthy Aging Adults
University of Connecticut
- Location
- Storrs, CT
- Eligibility basics
- Ages 50–75
- RecruitingHealthy volunteers
Automated IADL Sensing to Refine Measurement of Older Adult Daily Activity
University of Pittsburgh
- Location
- Pittsburgh, PA
- Eligibility basics
- Ages 75+ · Women only
- RecruitingHealthy volunteers
Multidimensional Predictive Modeling to Understand Mechanisms of Exercise Response Heterogeneity in Older Adults (M3AX)
Florida Institute for Human and Machine Cognition
- Location
- Pensacola, FL + 1 other US site
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteers
AMD and Validation Rod-Meditated Dark Adaptation With Everyday Task Performance
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 50–89
- RecruitingHealthy volunteersPhase 4
Characterization of the Serotonin 2A Receptor Selective PET Tracer [18F]MH.MZ in Patients With Neurodegenerative Diseases
Vanderbilt University Medical Center
- Location
- Nashville, TN
- Eligibility basics
- Ages 50–85
- RecruitingHealthy volunteers
LUNG-07: Advancing Precision-Based Lung Cancer Screening: Implementation, AI-Guided Risk Stratification, and Biomarker Integration (CREST AI)
University of Illinois at Chicago
- Location
- Chicago, IL + 1 other US site
- Eligibility basics
- Ages 50–80
- RecruitingHealthy volunteers
Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years
Kaiser Permanente
- Location
- Oakland, CA
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
A Comparison of Neuromuscular Recruitment in Trained and Untrained Adults
Mayo Clinic
- Location
- Rochester, MN
- Eligibility basics
- Ages 60–85
- RecruitingHealthy volunteers
Pain With Dementia
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
BabaCare: Testing a Care Copilot
Johns Hopkins University
- Location
- Baltimore, MD
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
Autoimmune Features of Neurodegenerative Disorders
Columbia University
- Location
- New York, NY
- Eligibility basics
- Ages 55–90
- RecruitingHealthy volunteers
Neural Control of Gait & Navigation in ADRD
University of Florida
- Location
- Gainesville, FL
- Eligibility basics
- Ages 65–89
- RecruitingHealthy volunteers
Effect of Daily Mixed Spice Consumption on Memory Function
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 50–80
- RecruitingHealthy volunteers
Inspiring Seniors Towards Exercise Promotion - 2
Emory University
- Location
- Atlanta, GA
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
Theory-Driven Manualized Approach to Improving New Learning and Memory in Healthy Aging and MCI
Kessler Foundation
- Location
- East Hanover, NJ
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteers
tVNS During Motor Training in Older Adults
Georgia Institute of Technology
- Location
- Atlanta, GA
- Eligibility basics
- Ages 65–84
- RecruitingHealthy volunteers
Memory Enhancement in Aging With Optimal Dosing
Boston University Charles River Campus
- Location
- Boston, MA
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
Digital Health Implementation Strategies to Improve Lung Cancer Screening Among Safety-Net Clinics
University of Utah
- Location
- Salt Lake City, UT
- Eligibility basics
- Ages 50–80
Questions
If I fit this group, will I qualify?
Not necessarily. Age and sex limits are only the first filter. Each study has its own inclusion and exclusion criteria, and the research team decides at screening.
Where do these age and sex limits come from?
From the eligibility section of each study’s official ClinicalTrials.gov record. We don’t infer eligibility from anything else.